Brain: normal variations and benign findings in fluorodeoxyglucose-PET/computed tomography imaging.
| Publication Type | Review |
| Authors | Berti V, Mosconi L, Pupi A |
| Journal | PET Clin |
| Volume | 9 |
| Issue | 2 |
| Pagination | 129-40 |
| Date Published | 04/01/2014 |
| ISSN | 1879-9809 |
| Keywords | Brain, Fluorodeoxyglucose F18, Multimodal Imaging, Positron-Emission Tomography, Radiopharmaceuticals, Tomography, X-Ray Computed |
| Abstract | Brain 18F-fluorodeoxyglucose (18F-FDG) PET allows the in vivo study of cerebral glucose metabolism, reflecting neuronal and synaptic activity. 18F-FDG-PET has been extensively used to detect metabolic alterations in several neurologic diseases compared with normal aging. However, healthy subjects have variants of 18F-FDG distribution, especially as associated with aging. This article focuses on 18F-FDG-PET findings in so-called normal brain aging, and in particular on metabolic differences occurring with aging and as a function of people’s gender. The effect of different substances, medications, and therapy procedures are discussed, as well as common artifacts. |
| DOI | 10.1016/j.cpet.2013.10.006 |
| PubMed ID | 24772054 |
| PubMed Central ID | PMC3998066 |