Brain PET Imaging: Approach to Cognitive Impairment and Dementia.

Publication Type	Review
Authors	Spano M, Roytman M, Aboian M, Saboury B, Franceschi A, Chiang G
Journal	PET Clin
Volume	18
Issue	1
Pagination	103-113
Date Published	01/01/2023
ISSN	1879-9809
Keywords	Cognitive Dysfunction, Alzheimer Disease
Abstract	Alzheimer disease (AD) is the most common cause of dementia, accounting for 50% to 60% of cases and affecting nearly 6 million people in the United States. Definitive diagnosis requires either antemortem brain biopsy or postmortem autopsy. However, clinical neuroimaging has been playing a greater role in the diagnosis and management of AD, and several PET tracers approach the sensitivity of tissue diagnosis in identifying AD pathologic condition. This review will focus on the utility of PET imaging in the setting of cognitive impairment, with an emphasis on its role in the diagnosis of AD.
DOI	10.1016/j.cpet.2022.09.006
PubMed ID	36442959
PubMed Central ID	PMC9713600