Weill Cornell Medicine
Citigroup Biomedical Imaging Center
Weill Cornell Medicine
Citigroup Biomedical Imaging Center

Functional neuroimaging in geriatric depression.

Publication Type Review
Authors Gunning F, Smith G
Journal Psychiatr Clin North Am
Volume 34
Issue 2
Pagination 403-22, viii
Date Published 04/08/2011
ISSN 1558-3147
Keywords Aging, Brain, Depressive Disorder, Magnetic Resonance Spectroscopy
Abstract Abnormalities in specific cerebral networks likely confer vulnerability that increases the susceptibility for development of geriatric depression and affect the course of symptoms. Functional neuroimaging enables the in vivo identification of alterations in cerebral function that characterize disease vulnerability and contribute to variability in depressive symptoms and antidepressant response. Judicious use of functional neuroimaging tools can advance pathophysiologic models of geriatric depression. Furthermore, geriatric depression provides a logical context within which to study the role of specific functional abnormalities in both antidepressant response and key behavioral and cognitive abnormalities of mood disorders.
DOI 10.1016/j.psc.2011.02.010
PubMed ID 21536165
PubMed Central ID PMC3339150
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