[68Ga]-DOTATATE PET/MRI in the diagnosis and management of recurrent head and neck paraganglioma with spinal metastasis.

Publication Type	Case Report
Authors	Kim S, Roytman M, Kamen E, Skafida M, Strauss S, Lin E, Kutler D, Zan E, Ivanidze J
Journal	Clin Imaging
Volume	79
Pagination	314-318
Date Published	08/08/2021
ISSN	1873-4499
Keywords	Paraganglioma, Spinal Neoplasms
Abstract	Most head and neck paragangliomas (PGLs) are biochemically silent and often present with recurrence and metastases in association with hereditary syndromes. Whole-body functional imaging is increasingly used to detect tumor extent and guide treatment planning of PGLs. [68Ga]-DOTATATE, which targets somatostatin receptor 2 (SSTR2) overexpression, has emerged as a sensitive functional imaging modality in PGLs. We present a patient with metastatic glomus caroticum PGL in whom [68Ga]-DOTATATE PET/MRI provided a more accurate characterization of metastatic extent, as compared to gadolinium-enhanced MRI of the neck and whole body [18F]-FDG PET/CT. We then review the current literature and discuss the imaging implications of [68Ga]-DOTATATE PET/MRI in PGLs.
DOI	10.1016/j.clinimag.2021.07.028
PubMed ID	34392071