[68Ga]-DOTATATE PET/MRI in the diagnosis and management of recurrent head and neck paraganglioma with spinal metastasis.
| Publication Type | Case Report |
| Authors | Kim S, Roytman M, Kamen E, Skafida M, Strauss S, Lin E, Kutler D, Zan E, Ivanidze J |
| Journal | Clin Imaging |
| Volume | 79 |
| Pagination | 314-318 |
| Date Published | 08/08/2021 |
| ISSN | 1873-4499 |
| Keywords | Paraganglioma, Spinal Neoplasms |
| Abstract | Most head and neck paragangliomas (PGLs) are biochemically silent and often present with recurrence and metastases in association with hereditary syndromes. Whole-body functional imaging is increasingly used to detect tumor extent and guide treatment planning of PGLs. [68Ga]-DOTATATE, which targets somatostatin receptor 2 (SSTR2) overexpression, has emerged as a sensitive functional imaging modality in PGLs. We present a patient with metastatic glomus caroticum PGL in whom [68Ga]-DOTATATE PET/MRI provided a more accurate characterization of metastatic extent, as compared to gadolinium-enhanced MRI of the neck and whole body [18F]-FDG PET/CT. We then review the current literature and discuss the imaging implications of [68Ga]-DOTATATE PET/MRI in PGLs. |
| DOI | 10.1016/j.clinimag.2021.07.028 |
| PubMed ID | 34392071 |