Publication Type	Case Report
Authors	Kim S, Roytman M, Kamen E, Skafida M, Strauss S, Lin E, Kutler D, Zan E, Ivanidze J
Journal	Clin Imaging
Volume	79
Pagination	314-318
Date Published	08/08/2021
ISSN	1873-4499
Keywords	Paraganglioma, Spinal Neoplasms
Abstract	Most head and neck paragangliomas (PGLs) are biochemically silent and often present with recurrence and metastases in association with hereditary syndromes. Whole-body functional imaging is increasingly used to detect tumor extent and guide treatment planning of PGLs. [68Ga]-DOTATATE, which targets somatostatin receptor 2 (SSTR2) overexpression, has emerged as a sensitive functional imaging modality in PGLs. We present a patient with metastatic glomus caroticum PGL in whom [68Ga]-DOTATATE PET/MRI provided a more accurate characterization of metastatic extent, as compared to gadolinium-enhanced MRI of the neck and whole body [18F]-FDG PET/CT. We then review the current literature and discuss the imaging implications of [68Ga]-DOTATATE PET/MRI in PGLs.
DOI	10.1016/j.clinimag.2021.07.028
PubMed ID	34392071