Publication Type Academic Article
Authors Convit A, de Leon M, Hoptman M, Tarshish C, De Santi S, Rusinek H
Journal Psychiatr Q
Volume 66
Issue 4
Pagination 343-55
Date Published 01/01/1995
ISSN 0033-2720
Keywords Aging, Magnetic Resonance Imaging, Temporal Lobe
Abstract The volume of temporal lobe structures was examined in twenty-seven older (mean age of 69.2 +/- 8.3 years) and ten younger subjects (mean age of 26.1 +/- 4.1 years) using quantitative magnetic resonance imaging (MRI) methods. Multiple regression analysis, using gender, overall atrophy, and head size as covariates, showed unique contributions of age to variance in both medial and lateral temporal lobe volumes. Temporal lobe subregions that showed the strongest unique age-related reductions were the hippocampus, fusiform gyrus, and parahippocampus. These results suggest age-related reductions in temporal lobe subvolumes.
DOI 10.1007/BF02238754
PubMed ID 8584590
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