Publication Type Academic Article
Authors Schiff N, Diringer M, Diserens K, Edlow B, Gosseries O, Hill N, Hochberg L, Ismail F, Meyer I, Mikell C, Mofakham S, Molteni E, Polizzotto L, Shah S, Stevens R, Thengone D
Journal Neurocrit Care
Volume 41
Issue 1
Pagination 129-145
Date Published 01/29/2024
ISSN 1556-0961
Keywords Brain-Computer Interfaces, Consciousness Disorders
Abstract BACKGROUND: We developed a gap analysis that examines the role of brain-computer interfaces (BCI) in patients with disorders of consciousness (DoC), focusing on their assessment, establishment of communication, and engagement with their environment. METHODS: The Curing Coma Campaign convened a Coma Science work group that included 16 clinicians and neuroscientists with expertise in DoC. The work group met online biweekly and performed a gap analysis of the primary question. RESULTS: We outline a roadmap for assessing BCI readiness in patients with DoC and for advancing the use of BCI devices in patients with DoC. Additionally, we discuss preliminary studies that inform development of BCI solutions for communication and assessment of readiness for use of BCIs in DoC study participants. Special emphasis is placed on the challenges posed by the complex pathophysiologies caused by heterogeneous brain injuries and their impact on neuronal signaling. The differences between one-way and two-way communication are specifically considered. Possible implanted and noninvasive BCI solutions for acute and chronic DoC in adult and pediatric populations are also addressed. CONCLUSIONS: We identify clinical and technical gaps hindering the use of BCI in patients with DoC in each of these contexts and provide a roadmap for research aimed at improving communication for adults and children with DoC, spanning the clinical spectrum from intensive care unit to chronic care.
DOI 10.1007/s12028-023-01924-w
PubMed ID 38286946
PubMed Central ID PMC11284251
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