Brain: normal variations and benign findings in fluorodeoxyglucose-PET/computed tomography imaging.

Publication Type	Review
Authors	Berti V, Mosconi L, Pupi A
Journal	PET Clin
Volume	9
Issue	2
Pagination	129-40
Date Published	04/01/2014
ISSN	1879-9809
Keywords	Brain, Fluorodeoxyglucose F18, Multimodal Imaging, Positron-Emission Tomography, Radiopharmaceuticals, Tomography, X-Ray Computed
Abstract	Brain 18F-fluorodeoxyglucose (18F-FDG) PET allows the in vivo study of cerebral glucose metabolism, reflecting neuronal and synaptic activity. 18F-FDG-PET has been extensively used to detect metabolic alterations in several neurologic diseases compared with normal aging. However, healthy subjects have variants of 18F-FDG distribution, especially as associated with aging. This article focuses on 18F-FDG-PET findings in so-called normal brain aging, and in particular on metabolic differences occurring with aging and as a function of people’s gender. The effect of different substances, medications, and therapy procedures are discussed, as well as common artifacts.
DOI	10.1016/j.cpet.2013.10.006
PubMed ID	24772054
PubMed Central ID	PMC3998066