Publication Type Review
Authors Berti V, Mosconi L, Pupi A
Journal PET Clin
Volume 9
Issue 2
Pagination 129-40
Date Published 04/01/2014
ISSN 1879-9809
Keywords Brain, Fluorodeoxyglucose F18, Multimodal Imaging, Positron-Emission Tomography, Radiopharmaceuticals, Tomography, X-Ray Computed
Abstract Brain 18F-fluorodeoxyglucose (18F-FDG) PET allows the in vivo study of cerebral glucose metabolism, reflecting neuronal and synaptic activity. 18F-FDG-PET has been extensively used to detect metabolic alterations in several neurologic diseases compared with normal aging. However, healthy subjects have variants of 18F-FDG distribution, especially as associated with aging. This article focuses on 18F-FDG-PET findings in so-called normal brain aging, and in particular on metabolic differences occurring with aging and as a function of people’s gender. The effect of different substances, medications, and therapy procedures are discussed, as well as common artifacts.
DOI 10.1016/j.cpet.2013.10.006
PubMed ID 24772054
PubMed Central ID PMC3998066
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