Publication Type Academic Article
Authors McEwen B, de Leon MJ , Lupien S, Meaney M
Journal Trends Endocrinol Metab
Volume 10
Issue 3
Pagination 92-96
Date Published 04/01/1999
ISSN 1879-3061
Abstract The hippocampal region of the brain is a useful model system for understanding the plasticity and resilience of brain cells to stress hormone action and aging. Hippocampal neurons show both structural and functional plasticity, and individual differences in hippocampal function are shaped by early life experiences. For human brain aging, there are new non-invasive imaging tools to relate to the animal models, and these can help to assess the vulnerability of the aging hippocampus in relation to stress and Alzheimer's disease.
DOI 10.1016/s1043-2760(98)00122-2
PubMed ID 10322401
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