Imaging Glioblastoma Posttreatment: Progression, Pseudoprogression, Pseudoresponse, Radiation Necrosis.

Publication Type	Review
Authors	Strauss S, Meng A, Ebani E, Chiang G
Journal	Radiol Clin North Am
Volume	57
Issue	6
Pagination	1199-1216
Date Published	08/16/2019
ISSN	1557-8275
Keywords	Brain Neoplasms, Diagnostic Imaging, Glioblastoma, Radiation Injuries
Abstract	Radiographic monitoring of posttreatment glioblastoma is important for clinical trials and determining next steps in management. Evaluation for tumor progression is confounded by the presence of treatment-related radiographic changes, making a definitive determination less straight-forward. The purpose of this article was to describe imaging tools available for assessing treatment response in glioblastoma, as well as to highlight the definitions, pathophysiology, and imaging features typical of true progression, pseudoprogression, pseudoresponse, and radiation necrosis.
DOI	10.1016/j.rcl.2019.07.003
PubMed ID	31582045