Weill Cornell Medicine
Citigroup Biomedical Imaging Center
Weill Cornell Medicine
Citigroup Biomedical Imaging Center

Imaging Glioblastoma Posttreatment: Progression, Pseudoprogression, Pseudoresponse, Radiation Necrosis.

Publication Type Review
Authors Strauss S, Meng A, Ebani E, Chiang G
Journal Neuroimaging Clin N Am
Volume 31
Issue 1
Pagination 103-120
Date Published 02/01/2021
ISSN 1557-9867
Keywords Brain Neoplasms, Diagnostic Imaging, Glioblastoma, Radiation Injuries
Abstract Radiographic monitoring of posttreatment glioblastoma is important for clinical trials and determining next steps in management. Evaluation for tumor progression is confounded by the presence of treatment-related radiographic changes, making a definitive determination less straight-forward. The purpose of this article was to describe imaging tools available for assessing treatment response in glioblastoma, as well as to highlight the definitions, pathophysiology, and imaging features typical of true progression, pseudoprogression, pseudoresponse, and radiation necrosis.
DOI 10.1016/j.nic.2020.09.010
PubMed ID 33220823
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