Publication Type | Academic Article |
Authors | Solomonov N |
Journal | Psychiatry Res |
Volume | 329 |
Pagination | 115469 |
Date Published | 09/10/2023 |
ISSN | 1872-7123 |
Keywords | Depression, Psychotherapy |
Abstract | Psychotherapies are effective in reducing late-life depression. Yet, about half of patients remain depressed at treatment end. Advances in neuroscience can inform simplified interventions that target key brain networks impacted by depression. Behavioral activation therapies that increase social connectedness may improve social reward responsivity and alter abnormalities of the Positive Valence System (PVS). Engage & Connect is an example for a scalable and simple neuroscience-informed psychotherapy, aimed to improve PVS functions and social reward responsivity by increasing engagement in rewarding social activities. Interventions that improve social reward responsivity can be promising first-line treatments for late-life depression in the community. |
DOI | 10.1016/j.psychres.2023.115469 |
PubMed ID | 37783093 |
PubMed Central ID | PMC10841452 |