PET/CT in diagnosis of movement disorders.

Publication Type	Review
Authors	Berti V, Pupi A, Mosconi L
Journal	Ann N Y Acad Sci
Volume	1228
Pagination	93-108
Date Published	06/01/2011
ISSN	1749-6632
Keywords	Movement Disorders, Positron-Emission Tomography, Tomography, Emission-Computed
Abstract	Molecular imaging with PET offers a broad variety of tools supporting the diagnosis of movement disorders. The more widely applied PET imaging techniques have focused on the assessment of neurotransmitter systems, predominantly the pre- and postsynaptic dopaminergic system. Additionally, PET imaging with [(18) F]fluorodeoxyglucose has been extensively used to assess local synaptic activity in the resting state and to highlight local changes in brain metabolism accompanying changes in neural activity in movement disorders. PET imaging has provided us with diagnostic agents as well as tools for evaluation of novel therapeutics, and has served as a powerful means for revealing in vivo changes at different stages of movement disorders and within the course of an individual patient's illness.
DOI	10.1111/j.1749-6632.2011.06025.x
PubMed ID	21718327
PubMed Central ID	PMC3692301