Publication Type Academic Article
Authors de Leon M, George A, Tomanelli J, Christman D, Kluger A, Miller J, Ferris S, Fowler J, Brodie J, van Gelder P
Journal Neurobiol Aging
Volume 8
Issue 4
Pagination 319-23
Date Published 01/01/1987
ISSN 0197-4580
Keywords Aging, Brain, Glucose, Tomography, Emission-Computed
Abstract Using PET VI and 11-CDG we replicated our earlier PET III and 18-FDG normal aging findings. Examination of young and old normal volunteers revealed the absence of any absolute regional age-related changes in glucose utilization. For the combined sample (N = 81) we did find evidence to suggest a relative hypofrontal change with increasing age. A strong relationship between age and ventricular size (CT) was also found. These findings suggest the preserved glucose metabolism of the resting aging brain in the presence of structural atrophic changes.
DOI 10.1016/0197-4580(87)90070-4
PubMed ID 3498127
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