Publication Type | Academic Article |
Authors | de Leon M, George A, Tomanelli J, Christman D, Kluger A, Miller J, Ferris S, Fowler J, Brodie J, van Gelder P |
Journal | Neurobiol Aging |
Volume | 8 |
Issue | 4 |
Pagination | 319-23 |
Date Published | 01/01/1987 |
ISSN | 0197-4580 |
Keywords | Aging, Brain, Glucose, Tomography, Emission-Computed |
Abstract | Using PET VI and 11-CDG we replicated our earlier PET III and 18-FDG normal aging findings. Examination of young and old normal volunteers revealed the absence of any absolute regional age-related changes in glucose utilization. For the combined sample (N = 81) we did find evidence to suggest a relative hypofrontal change with increasing age. A strong relationship between age and ventricular size (CT) was also found. These findings suggest the preserved glucose metabolism of the resting aging brain in the presence of structural atrophic changes. |
DOI | 10.1016/0197-4580(87)90070-4 |
PubMed ID | 3498127 |