Progress and prospects: gene therapy clinical trials (part 1).

Publication Type	Review
Authors	Alexander B, Ali R, Alton E, Bainbridge J, Braun S, Cheng S, Flotte T, Gaspar H, Grez M, Griesenbach U, Kaplitt M, Ott M, Seger R, Simons M, Thrasher A, Thrasher A, Ylä-Herttuala S
Journal	Gene Ther
Volume	14
Issue	20
Pagination	1439-47
Date Published	10/01/2007
ISSN	0969-7128
Keywords	Clinical Trials as Topic, Genetic Therapy
Abstract	Over the last two decades gene therapy has moved from preclinical to clinical studies for many diseases ranging from single gene disorders such as cystic fibrosis and Duchenne muscular dystrophy, to more complex diseases such as cancer and cardiovascular disorders. Gene therapy for severe combined immunodeficiency (SCID) is the most significant success story to date, but progress in many other areas has been significant. We asked 20 leaders in the field succinctly to summarize and comment on clinical gene therapy research in their respective areas of expertise and these are published in two parts in the Progress and Prospect series.
DOI	10.1038/sj.gt.3303001
PubMed ID	17909539