QSM Throughout the Body.

Publication Type	Review
Authors	Dimov A, Li J, Nguyen T, Roberts A, Spincemaille P, Straub S, Zun Z, Prince M, Wang Y
Journal	J Magn Reson Imaging
Volume	57
Issue	6
Pagination	1621-1640
Date Published	02/07/2023
ISSN	1522-2586
Keywords	Magnetic Resonance Imaging, Algorithms
Abstract	Magnetic materials in tissue, such as iron, calcium, or collagen, can be studied using quantitative susceptibility mapping (QSM). To date, QSM has been overwhelmingly applied in the brain, but is increasingly utilized outside the brain. QSM relies on the effect of tissue magnetic susceptibility sources on the MR signal phase obtained with gradient echo sequence. However, in the body, the chemical shift of fat present within the region of interest contributes to the MR signal phase as well. Therefore, correcting for the chemical shift effect by means of water-fat separation is essential for body QSM. By employing techniques to compensate for cardiac and respiratory motion artifacts, body QSM has been applied to study liver iron and fibrosis, heart chamber blood and placenta oxygenation, myocardial hemorrhage, atherosclerotic plaque, cartilage, bone, prostate, breast calcification, and kidney stone.
DOI	10.1002/jmri.28624
PubMed ID	36748806
PubMed Central ID	PMC10192074