Publication Type Review
Authors Dimov A, Li J, Nguyen T, Roberts A, Spincemaille P, Straub S, Zun Z, Prince M, Wang Y
Journal J Magn Reson Imaging
Volume 57
Issue 6
Pagination 1621-1640
Date Published 02/07/2023
ISSN 1522-2586
Keywords Magnetic Resonance Imaging, Algorithms
Abstract Magnetic materials in tissue, such as iron, calcium, or collagen, can be studied using quantitative susceptibility mapping (QSM). To date, QSM has been overwhelmingly applied in the brain, but is increasingly utilized outside the brain. QSM relies on the effect of tissue magnetic susceptibility sources on the MR signal phase obtained with gradient echo sequence. However, in the body, the chemical shift of fat present within the region of interest contributes to the MR signal phase as well. Therefore, correcting for the chemical shift effect by means of water-fat separation is essential for body QSM. By employing techniques to compensate for cardiac and respiratory motion artifacts, body QSM has been applied to study liver iron and fibrosis, heart chamber blood and placenta oxygenation, myocardial hemorrhage, atherosclerotic plaque, cartilage, bone, prostate, breast calcification, and kidney stone.
DOI 10.1002/jmri.28624
PubMed ID 36748806
PubMed Central ID PMC10192074
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