Rapid monitoring of changes in water diffusion coefficients during reversible ischemia in cat and rat brain.

Publication Type Academic Article
Authors Davis D, Ulatowski J, Eleff S, Izuta M, Mori S, Shungu D, van Zijl P
Journal Magn Reson Med
Volume 31
Issue 4
Pagination 454-60
Date Published 04/01/1994
ISSN 0740-3194
Keywords Body Water, Brain, Brain Ischemia
Abstract Changes in the diffusion constant of water during reversible brain ischemia and cardiac arrest were monitored with a 10-s time resolution. Results (five cats, three rats) indicate that these changes are reversible and that the bulk of the changes are not caused by temperature or motion related to brain pulsations and blood flow. The rapid time course of the changes corresponds to the known time course for changes in energy state, signal transduction, and ionic homeostasis.
DOI 10.1002/mrm.1910310416
PubMed ID 8208123
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