Regional analysis of femoral head perfusion following displaced fractures of the femoral neck.

Publication Type Academic Article
Authors Dyke J, Lazaro L, Hettrich C, Hentel K, Helfet D, Lorich D
Journal J Magn Reson Imaging
Volume 41
Issue 2
Pagination 550-4
Date Published 12/12/2013
ISSN 1522-2586
Keywords Femoral Neck Fractures, Femur Head, Magnetic Resonance Imaging
Abstract PURPOSE: To assess regional variations in the arterial and venous blood supply to the femoral head following displaced fracture of the femoral neck using dynamic contrast enhanced (DCE)-MRI quadrant analysis. MATERIALS AND METHODS: A total of 27 subjects with displaced femoral neck fractures were enrolled in the study. Quadrant specific DCE-MRI perfusion analysis was performed on a 1.5 Tesla MRI scanner. Simultaneous imaging of control and displaced fractured hips was done for comparison. RESULTS: Quadrant specific decreases were found in the arterial (A (0.52 versus 0.27; P = 5.7E-13), Akep (1.0/min(-1) versus 0.41/min(-1) ; P = 1.3E-9) and venous (kel (0.05/min(-1) versus -0.02/min(-1) ; P = 5.1E-5) supply to the femoral head between control and injured sides using a two-factor analysis of variance test. The fractional perfusion (initial area under the curve) in the supero/inferolateral quadrants was 49% min/54% min, in the supero/inferomedial quadrants was 43% min/46% min and for the total femoral head was 39% min on the fracture versus control sides. CONCLUSION: Quadrant specific decreases in arterial and venous perfusion on the fracture side were observed when compared with control.
DOI 10.1002/jmri.24524
PubMed ID 24338938
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