Publication Type Academic Article
Authors Balloon D, Mahmood U, Jakubowski A, Koutcher J
Journal Magn Reson Med
Volume 30
Issue 6
Pagination 754-8
Date Published 12/01/1993
ISSN 0740-3194
Keywords Magnetic Resonance Spectroscopy
Abstract A technique is described which reduced the magnetic susceptibility induced line broadening in NMR spectra obtained from three biological systems at 4.7 Tesla. Proton spectra from a sealed suspension of HL60 leukemic myeloblasts yielded minimum linewidths of 1.3 Hz at 200 MHz (0.0065 ppm) after 10 min of automated shimming. 31P spectra from an in vivo murine MCa mammary carcinoma yielded a well-resolved phosphorylcholine resonance without proton decoupling and with the resistive shim coil currents set to zero. 31P spectra from a perfused suspension of RIF-1 fibrosarcoma cells exhibited a gamma-nucleoside triphosphate resonance which was resolved into purine and pyrimidine components.
DOI 10.1002/mrm.1910300615
PubMed ID 8139459
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