Publication Type Academic Article
Authors Wolf O, Dyakin V, Vadasz C, de Leon M, McEwen B, Bulloch K
Journal Brain Res Brain Res Protoc
Volume 10
Issue 1
Pagination 41-6
Date Published 08/01/2002
ISSN 1385-299X
Keywords Brain Mapping, Gyrus Cinguli, Hippocampus, Lateral Ventricles, Magnetic Resonance Imaging, Rats, Sprague-Dawley
Abstract MRI imaging of the rodent brain is a rapidly growing field in the neurosciences. Relatively limited information is available for regional volume determination. The present paper describes a reliable method for the assessment of the hippocampus, the anterior cingulate cortex, the retrosplenial granular cortex and the ventricles in rats. MRI scans were acquired using a 7 T magnet. The anatomical sampling method was found to be highly reliable with an intra-rater reliability of greater than 0.93. The current protocol should facilitate future in vivo neuroimaging research using animal models of neurodegenerative diseases.
DOI 10.1016/s1385-299x(02)00181-2
PubMed ID 12379436
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